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GUGUTS

Fractyl Health, Inc.

Hot onWhy it's trendingX chatter spiked vs its recent normPrice and volume picking up
$GUTS·$57M·Biotechnology·Healthcare
$0.81-5.2%YTD-63.2%1Y-54.7%
Mentions · last 7 days
2026-07-10: 5 posts2026-07-11: 6 posts2026-07-12: 11 posts2026-07-13: 32 posts2026-07-14: 16 posts2026-07-15: 86 posts2026-07-16: 50 posts206+53%
Price updated 4h ago·X counts updated 1d ago
GUGUTS
$GUTSFractyl Health, Inc.
$0.81-5.19%206 posts+53%
AI analysisFundamentalsVoices on X
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AI verdict & sentimentAI analysisGenerated by AI from underlying data

Top X posts

Today's AI verdict on what's driving $GUTS, plus how loud the X conversation is and which way it's leaning.

AI analysis

TickerTalks’ read on the fundamentals and what’s driving the move.

Driven by hypeWinding up for a moveAI verdict · as of 2026-07-16

Trading in a tight range and building pressure — a move looks likely soon, but the direction isn't clear yet.

Fractyl Health up 14% today on positive REMAIN-1 data — Revita device helps maintain weight after GLP-1 stop.

Fractyl Health is developing Revita, a duodenal metabolic therapy device — a minimally-invasive procedure that resurfaces the intestinal lining to treat obesity and type-2 diabetes. The stock is up 14% today on positive REMAIN-1 one-year data.

  • Revenue is essentially zero — this is a clinical-stage biotech/medtech; the equity value depends on Revita commercial progression plus the RJV001/RJV002 gene-therapy pipeline.
  • The July 15 REMAIN-1 Midpoint Cohort data showing durable weight maintenance after GLP-1 discontinuation is a real clinical-progress signal — this is exactly the market gap Fractyl is targeting.
  • The 'stock has doubled from $0.40-plus' framing captures the volatility profile; the current $0.91 level is still near lows despite the recent bounce.
  • Over 90% participant retention and medication-resumption rates below modeled assumptions signals strong Phase 3-adjacent clinical execution — real proof-points for the Revita commercialization narrative.
  • Zero insider transactions in the last 30 days at 26th percentile of 52-week range — clean absence of distributing signal even as the tape has recovered.

August 11 Q2 earnings plus continued Revita pivotal-cohort data is the specific catalyst: revenue-timing commentary plus a specific commercial-launch guide is what continues the run; a durability concern in the pivotal cohort or additional dilutive raise is where the +14% today gives back. Real obesity-plus-diabetes medtech play with real REMAIN-1 clinical validation — the setup is asymmetric event-heavy.

Agrees with X sentimentThe bullish X take on the REMAIN-1 pivotal cohort progression, the >90% participant retention, and the H2 2026 major catalyst framing is analytically fair. The RJV001/RJV002 gene-therapy program adds real pipeline optionality; today's +14% on the REMAIN-1 data validates the momentum.

What to watch: Aug 11 Q2 earnings plus continued Revita pivotal-cohort data — need specific commercial-launch guide. A durability concern in the pivotal cohort or additional dilutive raise is where the +14% today gives back.

On the calendar: 2026-08-11 — Q2 earnings

X sentiment

What the X crowd is saying right now — descriptive, summarised from the day’s posts.

Bullish sentiment7 posts analyzed · as of 2026-07-17

Fractyl Health delivered decisive positive data. The REMAIN-1 Midpoint Cohort demonstrated Revita-mediated durable and substantial weight retention at one year after GLP-1 discontinuation without maintenance therapy. Morgan Stanley views the one-year data as encouraging ahead of the key topline REMAIN-1 Pivotal Cohort readout expected in early Q4 2026 and maintains a $2 price target. HC Wainwright reiterated Buy at $8. A potential FDA De Novo application submission is targeted for late Q4 2026. Bulls describe REMAIN-1 as a weight-maintenance breakthrough for post-GLP-1 patients and are stumped why the stock is not >$1.25 given approval seems now ~80% de-risked with a large conservative TAM. Bulls are holding long positions. There is no substantive bear thread in the sample; sentiment is uniformly constructive.

Read the AI verdict + X sentiment for $GUTS

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What it does

Plain-English summary of the business — what they sell and how they make money.

Develops the Revita duodenal mucosal resurfacing procedure targeting type 2 diabetes and obesity without systemic drugs.

Industry overviewAI analysisGenerated by AI from underlying data

Where Biotechnology sits in its cycle right now — and what that implies for $GUTS.

Biotechnology · Healthcare

No material change from last week — ADA conference oral formulation competition is bifurcating biotech multiples between GLP-1 platform holders and precision oncology innovators.

What this means for $GUTS

Partial — Develops the Revita duodenal mucosal resurfacing procedure targeting type 2 diabetes and obesity without systemic drugs; the GLP-1 pipeline bifurcation and ADA oral formulation competition is a secondary rather than primary near-term earnings catalyst.

Top industry ETF

$IBBiShares Biotechnology ETF
+11.9%YTD
+44.0%1Y

Fundamentals & catalyst

Profitability, valuation, and the next earnings event — at a glance, with rule-of-thumb signals.

Key ratios

P/E
-0.5How much investors are paying per dollar of profit the company actually earned in the last 12 months. Lower means the stock looks cheaper relative to earnings.~15–25 is typical for the S&P 500; high-growth names trade 30+; hyper-growth or speculative can be 100+ or negative.
ROIC
-104%What percentage return the business earns on every dollar of capital (equity + debt) deployed in operations. The cleanest measure of business quality.Above ~15% is high-quality; consistently above 25% suggests a real moat. Below the company's cost of capital is value-destroying.
Op margin
0.0%Operating profit (after sales, marketing, R&D, and overhead but before interest and taxes) as a percentage of revenue. The clearest view of how well the underlying business is run.Mature business above 20% is healthy; software businesses can run 30%+; commodity / retail businesses operate in single digits.
FCF yield
-179%Free cash flow (operating cash flow minus capex) divided by the company's market cap. The cash-on-cash return you'd get owning the whole business at today's price.Above ~5% is attractive; below ~2% means you're paying up for growth. Capital-light businesses (software) run higher than capital-heavy ones (utilities).
P/S
0.0Same idea as P/E but per dollar of revenue. Useful for companies that aren't profitable yet, where P/E is meaningless.Under ~2 is cheap; software / SaaS often runs 8–15; well above 20 implies the market is pricing in very high future growth.
ROE
-45.7%Net income as a percentage of shareholders' equity. Similar to ROIC but counts only the equity side.Above 20% is strong, but can be inflated by leverage — a heavily indebted company can show high ROE with weak underlying ROIC.
Gross margin
0.0%Revenue minus the direct cost of producing what was sold, as a percentage of revenue. The first read on whether the product is structurally profitable.Software / SaaS is typically 70%+; consumer goods 30–50%; commodity / hardware businesses can be under 20%.
D/E
2.8Total debt divided by shareholders' equity. Measures how much the business runs on borrowed money versus owner capital.Under 1 is conservative; 1–2 is typical for mature businesses; over 2 is leveraged and more sensitive to interest rates.

Past earnings

QuarterReportedActualEstimateSurprise
Q1 2026May 12, 2026$-0.13$-0.17+23.5%
Q4 2025Mar 24, 2026$0.15$-0.19+178.9%
Q3 2025Nov 12, 2025$-0.35$-0.34-2.9%
Q2 2025Aug 12, 2025$-0.53$-0.37-43.2%
Next earningsTue, Aug 11·consensus EPS $-0.15

Quarterly trend

QuarterRevenueYoYGrossOpEPSFCF
Q1 FY26$0———$0.12$-22.5M
Q4 FY25$0-100.0%——$-0.58$-21.3M
Q3 FY25$0-100.0%——$-0.71$-22.7M
Q2 FY25$0-100.0%——$-0.57$-21.3M

Forward consensus

5-year forecast · up to 4 analysts
FYRevenueRangeEPSRangeAnalysts
FY26$12.4M$9.5M – $18.9M-$0.35-$0.40 – -$0.313
FY27$17.9M$13.7M – $27.3M-$0.49-$0.71 – -$0.332
FY28$78.1M$59.7M – $119.0M-$0.31-$0.34 – -$0.294
FY29$252.5M$192.8M – $384.5M$0.09$0.06 – $0.163
FY30$461.4M$352.3M – $702.7M$0.62$0.43 – $1.043

Setup & momentum

Volume, range, and moving-average position — the technical setup driving short-term moves.

Right now

Vol vs 30dToday's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.0.8×Today's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.
52w rangeWhere the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.21%Where the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.
vs 50d MALatest close vs the 50-day simple moving average. Positive = short-term trend is up.+0.4%Latest close vs the 50-day simple moving average. Positive = short-term trend is up.
vs 200d MALatest close vs the 200-day simple moving average. Positive = long-term trend is up.-24.5%Latest close vs the 200-day simple moving average. Positive = long-term trend is up.

Float & profile

FloatLow float · 29.4M shFree-float shares — the slice of issued stock actually available to trade. Lower buckets squeeze harder on a catalyst.Traded today4.9% of floatToday's volume as a percent of the free float. Above 5% on a single day is unusually high turnover for the available share count.β2.295-year weekly beta vs the S&P 500. Above 1.5 means the stock typically moves more than the index; below 0.8 moves less.

Insider activity

Recent open-market buys and sells by officers and directors — flagged when multiple insiders cluster.

Recent transactions

BuyJun 12Ajay RoyanDirector23.0K sh$20KBuyJun 10Harith RajagopalanCEO25.0K sh$18KBuyJun 10William BradleyDirector68.5K sh$50KBuyJun 10Ian SheffieldDirector35.0K sh$26KBuyJun 8Smith Weber LaraCFO20.0K sh$14K
+ 8 other (8 awards) in window

See when $GUTS insiders are putting their own money in

  • Real-time open-market buys and sells from Form 4 filings
  • Cluster-buy detection when multiple insiders pile in at once
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SEC filings

Material 8-K, 13D, S-3, and 424B5 events from the last 180 days — the filings that actually move the price.

Recent material filings

8-KPress release / Reg FDJul 158-K — Item 7.01: Press release / Reg FD · Item 8.01: Other event
AI summary

Fractyl Health (GUTS) disclosed one-year data from the REMAIN-1 Midpoint Cohort study for its Revita duodenal metabolic therapy device on July 15, 2026. The blinded, sham-controlled study demonstrated dose-dependent durability of weight maintenance at one year following discontinuation of GLP-1 receptor agonist therapy. Data confirmed that the metabolic effect achieved with Revita persists after GLP-1 drugs are stopped, a key differentiator in the obesity/metabolic disease space. An investor webcast to present the data was held on July 15, 2026, at 8:00 a.m. Eastern Time.

8-KShareholder voteJun 118-K — Item 5.07: Shareholder vote
AI summary

Fractyl Health, Inc. (ticker GUTS) held its 2026 Annual Meeting on June 10, 2026, with ~70.7% of 158.6M eligible shares represented. Three Class II directors were elected for three-year terms: Marc Elia (65.2M For), Clive Meanwell (63.7M For), and Ian Sheffield (73.8M For, nearly unopposed); Ernst & Young LLP was ratified as independent auditor (107.9M For, 0.2M Against). All proposals passed. Routine governance with no contested items and modest opposition to the other two directors, consistent with normal institutional abstention patterns.

8-KPress release / Reg FDJun 48-K — Item 7.01: Press release / Reg FD · Item 8.01: Other event
AI summary

Fractyl Health, Inc. (GUTS) disclosed its addition to Nasdaq Global Market Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 under 8-K Item 8.01 (other events). Index inclusions are significant because they trigger automatic buying from passive index funds and ETFs that track the benchmark, often resulting in increased share price and trading volume. Index providers typically announce additions in advance of the effective rebalancing date, giving institutions time to adjust their holdings. The event increases GUTS's institutional ownership base and enhances its market visibility and liquidity profile.

8-KPress release / Reg FDMay 118-K — Item 7.01: Press release / Reg FD
AI summary

GUTS filed an 8-K Item 7.01 (Reg FD) disclosure dated 2026-05-11. Reg FD disclosures make material information simultaneously available to all investors; content may include guidance updates, strategic plans, or preliminary results.

8-KPress release / Reg FDMar 248-K — Item 2.02: Earnings release · Item 7.01: Press release / Reg FD
AI summary

GUTS reported period ending 2026-03-24 financial results (8-K Item 2.02). Investors should review the full earnings press release and any management guidance for forward outlook.

8-KListing / delisting noticeMar 178-K — Item 3.01: Listing / delisting notice
8-KPress release / Reg FDFeb 268-K — Item 7.01: Press release / Reg FD
8-KPress release / Reg FDJan 298-K — Item 7.01: Press release / Reg FD · Item 8.01: Other event
+ 12 other (6 13Gs · 2 proxys · 1 10-Q · 1 earnings 8-K) in window

Recent news

Latest headlines from major outlets, sourced and timestamped — context for whatever just moved.

Fractyl Health Stock Up on Encouraging One-Year Revita Study Resultszacks.com·2d agoFractyl Health, Inc. (GUTS) Discusses 1-Year REMAIN-1 Data Demonstrating Durable Weight Maintenance After GLP-1 Discontinuation Transcriptseekingalpha.com·2d agoFractyl Health Helps Maintain Weight After Stopping Popular Obesity Drugs, Stock Soarsbenzinga.com·3d agoFractyl Health Says Revita Helped Patients Keep Weight Off After Stopping GLP-1smarketbeat.com·3d agoFractyl Health Reports Positive Randomized Data from REMAIN-1 Midpoint Cohort Demonstrating Durable Weight Maintenance One Year After GLP-1 Discontinuationglobenewswire.com·3d ago

In themes

Explore the broader themes this ticker is being talked about under.

Trending on XGLP-1 & Weight LossGene Editing & CRISPR

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TickerTalks is a research tool, not financial advice. We surface social-attention data; we do not make stock recommendations. Past attention is not predictive of future price movements.

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