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ALALEC

Alector, Inc.

$ALEC·$198M·Biotechnology·Healthcare
$1.96-3.9%1Y+7.5%
Mentions · last 7 days
2026-08-07: 0 posts2026-08-08: 1 posts2026-08-09: 0 posts2026-08-10: 0 posts2026-08-11: 5 posts2026-08-12: 4 posts2026-08-13: 0 posts11+57%
Price updated 1d ago·X counts updated 2d ago
ALALEC
$ALECAlector, Inc.
$1.96-3.92%11 posts+57%
AI analysisFundamentalsVoices on X
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AI verdict & sentimentAI analysisGenerated by AI from underlying data

Top X posts

Today's AI verdict on what's driving $ALEC, plus how loud the X conversation is and which way it's leaning.

AI analysis

TickerTalks’ read on the fundamentals and what’s driving the move.

Broken storySelling offAI verdict · as of 2026-08-15

Falling on heavy selling — points lower unless it turns around.

Alector is the immuno-neurology biotech broken-tape +8% t12m — GSK partnership ENDED after dementia/Alzheimer's drug failures 7/8, Q2 rev -58% YoY.

Alector is a clinical-stage biopharma focused on immuno-neurology (innate immune-system programs for brain pathologies with a genetic root) — the equity is a broken-story name breaking down on the specific GSK partnership termination and the specific Alzheimer's drug failures.

  • 'Alector and GSK partnership to end after dementia, Alzheimer's drug failures' (Reuters 7/8) — real specific fact pattern of major clinical/commercial-partnership collapse.
  • Q2 was a beat: EPS -$0.21 vs -$0.23 (+8%), revenue $3.32M vs $1.71M (+94%) — the specific fact pattern of low-base beat on collapsing revenue.
  • 4 revenue-declining quarters: Q2 -58% YoY, Q1 -72%, Q4 -89%, Q3 -79% — real severe post-GSK revenue collapse.
  • Position at 38% of 52w with stock +16% above 50d MA and +6% above 200d MA — coiled tape mid-range drawdown, t12m +8%.
  • Fundamentals: -385% GM (loss-making at gross), -9% OM (loss-making), FCF yield -102% — deeply broken profitability.
  • Analyst EPS -$0.87 FY26 → -$0.62 FY27 → -$0.64 FY28 → -$0.37 FY29 with rev $6M → $26M FY27 → $3M FY28 — real severe post-GSK revenue collapse.

November 5 is the next print with -$0.24 EPS estimate — Alector's specific pipeline pivot without GSK partnership or specific new partnership commentary is the tape; the invalidator is a specific dilutive raise or additional pipeline setback. The real risk on $198M market-cap post-GSK collapse is that pipeline reset compounds with additional dilution.

What to watch: November 5 Q3 print — pipeline pivot post-GSK and any new partnership commentary. A specific new deal extends the coil; additional pipeline setback or dilution is the invalidator.

On the calendar: 2026-11-05 — Q3 earnings

no sentimentpartnership terminatedpipeline reset

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What it does

Plain-English summary of the business — what they sell and how they make money.

Clinical-stage immuno-neurology biotech developing innate immune therapies targeting neurodegeneration in Alzheimer's and related diseases.

Industry overviewAI analysisGenerated by AI from underlying data

Where Biotechnology sits in its cycle right now — and what that implies for $ALEC.

Biotechnology · Healthcare

No material change from last week — ADA conference oral formulation competition is bifurcating biotech multiples between GLP-1 platform holders and precision oncology innovators.

Top industry ETF

$IBBiShares Biotechnology ETF
+12.1%YTD
+44.4%1Y

Fundamentals & catalyst

Profitability, valuation, and the next earnings event — at a glance, with rule-of-thumb signals.

Key ratios

P/E
-1.7How much investors are paying per dollar of profit the company actually earned in the last 12 months. Lower means the stock looks cheaper relative to earnings.~15–25 is typical for the S&P 500; high-growth names trade 30+; hyper-growth or speculative can be 100+ or negative.
ROIC
-67.6%What percentage return the business earns on every dollar of capital (equity + debt) deployed in operations. The cleanest measure of business quality.Above ~15% is high-quality; consistently above 25% suggests a real moat. Below the company's cost of capital is value-destroying.
Op margin
-9.1%Operating profit (after sales, marketing, R&D, and overhead but before interest and taxes) as a percentage of revenue. The clearest view of how well the underlying business is run.Mature business above 20% is healthy; software businesses can run 30%+; commodity / retail businesses operate in single digits.
FCF yield
-103%Free cash flow (operating cash flow minus capex) divided by the company's market cap. The cash-on-cash return you'd get owning the whole business at today's price.Above ~5% is attractive; below ~2% means you're paying up for growth. Capital-light businesses (software) run higher than capital-heavy ones (utilities).
P/S
14.7Same idea as P/E but per dollar of revenue. Useful for companies that aren't profitable yet, where P/E is meaningless.Under ~2 is cheap; software / SaaS often runs 8–15; well above 20 implies the market is pricing in very high future growth.
ROE
-5.3%Net income as a percentage of shareholders' equity. Similar to ROIC but counts only the equity side.Above 20% is strong, but can be inflated by leverage — a heavily indebted company can show high ROE with weak underlying ROIC.
Gross margin
-385%Revenue minus the direct cost of producing what was sold, as a percentage of revenue. The first read on whether the product is structurally profitable.Software / SaaS is typically 70%+; consumer goods 30–50%; commodity / hardware businesses can be under 20%.
D/E
-3.3Total debt divided by shareholders' equity. Measures how much the business runs on borrowed money versus owner capital.Under 1 is conservative; 1–2 is typical for mature businesses; over 2 is leveraged and more sensitive to interest rates.

Past earnings

QuarterReportedActualEstimateSurprise
Q2 2026Aug 6, 2026$-0.21$-0.23+8.1%
Q1 2026May 7, 2026$-0.21$-0.35+40.0%
Q4 2025Feb 25, 2026$-0.34$-0.39+12.8%
Q3 2025Nov 6, 2025$-0.34$-0.42+19.0%
Next earningsThu, Nov 5·consensus EPS $-0.24

Quarterly trend

QuarterRevenueYoYGrossOpEPSFCF
Q2 FY26$3.3M-57.8%0.0%-735%$-0.21$-84.2M
Q1 FY26$1.0M-71.5%-99.2%-2411%$-0.21$-49.9M
Q4 FY25$6.2M-88.5%-420%-634%$-0.34$-41.7M
Q3 FY25$3.3M-78.8%-800%-1154%$-0.34$-32.5M

Forward consensus

5-year forecast · up to 6 analysts
FYRevenueRangeEPSRangeAnalysts
FY26$6.0M$4.0M – $6.9M-$0.87-$1.07 – -$0.756
FY27$26.2M$14.2M – $58.5M-$0.62-$0.79 – -$0.436
FY28$3.3M$1.8M – $7.5M-$0.64-$0.81 – -$0.375
FY29$2.8M$1.5M – $6.2M-$0.37-$0.96 – -$0.152
FY30$5.1M$2.8M – $11.3M-$0.23-$0.60 – -$0.092

Setup & momentum

Volume, range, and moving-average position — the technical setup driving short-term moves.

Right now

Vol vs 30dToday's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.0.7×Today's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.
52w rangeWhere the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.38%Where the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.
vs 50d MALatest close vs the 50-day simple moving average. Positive = short-term trend is up.+16.0%Latest close vs the 50-day simple moving average. Positive = short-term trend is up.
vs 200d MALatest close vs the 200-day simple moving average. Positive = long-term trend is up.+6.1%Latest close vs the 200-day simple moving average. Positive = long-term trend is up.

Float & profile

FloatMid float · 77.7M shFree-float shares — the slice of issued stock actually available to trade. Lower buckets squeeze harder on a catalyst.Traded today0.8% of floatToday's volume as a percent of the free float. Above 5% on a single day is unusually high turnover for the available share count.β0.585-year weekly beta vs the S&P 500. Above 1.5 means the stock typically moves more than the index; below 0.8 moves less.

Insider activity

Recent open-market buys and sells by officers and directors — flagged when multiple insiders cluster.

Recent transactions

SellApr 16Grace Wong-saradPrincipal Accounting Officer1.8K sh$5KSellMar 10Grace Wong-saradPrincipal Accounting Officer1.0K sh$3KSellMar 3Grace Wong-saradPrincipal Accounting Officer3.4K sh$7KSellMar 2Grace Wong-saradPrincipal Accounting Officer8.1K sh$17KSellMar 2Arnon RosenthalCEO81.9K sh$174KSellMar 2Berkley Neil LindsayCFO29.6K sh$63KSellFeb 26Grace Wong-saradPrincipal Accounting Officer4.1K sh$10K
+ 11 other (11 awards) in window

See when $ALEC insiders are putting their own money in

  • Real-time open-market buys and sells from Form 4 filings
  • Cluster-buy detection when multiple insiders pile in at once
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SEC filings

Material 8-K, 13D, S-3, and 424B5 events from the last 180 days — the filings that actually move the price.

Recent material filings

8-KAgreement terminatedJul 88-K — Item 1.02: Agreement terminated
AI summary

ALEC filed an 8-K (Items: 1.02) on 2026-07-08. Key content: The foregoing descriptions of the GSK Agreement and the Loan Agreement do not purport to be complete and are qualified in their entirety by reference to the full text of the GSK Agreement, a copy of which is filed as Exhibits 10.12 and 10.13 to the C. Financial figure noted: $10,428,827.77 . Materiality depends on the specific item codes and disclosed event.

8-KShareholder voteJun 178-K — Item 5.07: Shareholder vote
AI summary

ALEC filed an 8-K (Item 5.07) disclosing the results of stockholder voting at its annual or special meeting. Vote disclosures are routine governance filings; contested results (e.g., failed say-on-pay) would be the indicator of significance.

8-KMaterial agreementMay 78-K — Item 1.01: Material agreement
424B5Prospectus supplement (offering)May 7424B5
S-3Shelf registrationMar 12S-3
+ 17 other (4 13Gs · 3 earnings 8-Ks · 2 10-Qs · 2 proxys) in window

Recent news

Latest headlines from major outlets, sourced and timestamped — context for whatever just moved.

Alector (ALEC) Reports Q2 Loss, Tops Revenue Estimateszacks.com·9d agoAlector Reports Second Quarter 2026 Financial Results and Provides Business Updateglobenewswire.com·9d agoAlector and GSK partnership to end after dementia, Alzheimer's drug failuresreuters.com·38d ago

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