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KRKRYS

Krystal Biotech, Inc.

Strong FundamentalsStrong FundamentalsRevenue growing 32% YoY at strong marginsStreet coverage with positive forward estimatesQuiet on X (20 mentions/wk)
$KRYS·$9.6B·Biotechnology·Healthcare
$359.36+2.2%YTD+32.2%1Y+141.2%
Mentions · last 7 days
2026-08-22: 0 posts2026-08-23: 5 posts20-21%
Price updated 8h ago·X counts updated 8d ago
KRKRYS
$KRYSKrystal Biotech, Inc.
$359.36+2.25%20 posts-21%
AI analysisFundamentalsVoices on X
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AI verdict & sentimentAI analysisGenerated by AI from underlying data

Top X posts

Today's AI verdict on what's driving $KRYS, plus how loud the X conversation is and which way it's leaning.

AI analysis

TickerTalks’ read on the fundamentals and what’s driving the move.

Proven numbersAcceleratingAI verdict · as of 2026-08-31

The move is getting stronger, with heavier trading behind it.

Krystal Biotech is a rare profitable commercial-stage gene-therapy name — VYJUVEK is delivering, and the pipeline is the next leg.

Krystal Biotech (KRYS) sits in a category almost no small-cap biotech reaches — profitable, commercial, and still with pipeline optionality.

  • Q2 EPS beat consensus by ~5% on continued VYJUVEK uptake for dystrophic epidermolysis bullosa, with international launches beginning to layer on top of the US base.
  • Beyond VYJUVEK, the KB-series pipeline (respiratory, oncology, ophthalmology) using the same HSV-based redosable-gene-therapy platform is the multi-year rerating lever.
  • A recent director S-Sale of ~$8.2M by Rossi on August 14 is the kind of headline that always spooks retail — worth noting, but on a name of this scale it is typically diversification rather than a conviction signal.

Bottom line: commercial execution and pipeline breadth make this a bona fide fundamentals name in a space usually dominated by story stocks; watch VYJUVEK international ramp and KB-series readouts.

Agrees with X sentimentRetail biotech chatter is constructive on VYJUVEK and the platform; the numbers support the sentiment without validating specific price targets.

What to watch: Ex-US VYJUVEK launch progress (EU/Japan), KB-407 cystic fibrosis and KB-803 ophthalmology readouts, and any further insider transactions.

On the calendar: Q3 2026 earnings — typically reported in early November; date TBC.

X sentiment

What the X crowd is saying right now — descriptive, summarised from the day’s posts.

Bullish sentiment8 posts analyzed · as of 2026-08-10

Krystal Biotech posts frame Q2 as a pristine cash machine: revenue $119.2M up 24% year over year, net income $54.8M, gross margins at 95% and the balance sheet crossing $1.1B. VYJUVEK global revenue $119.2M and $965.9M since launch reinforce the durable-growth story, with brief pullback pressure.

Read the AI verdict + X sentiment for $KRYS

  • One-line verdict on what's driving the move — fundamentals, momentum, both, or an event
  • Next dated catalyst when there is one (earnings, deal closing, activist clock)
  • X crowd read with bullish/bearish call + post volume
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What it does

Plain-English summary of the business — what they sell and how they make money.

Sells Vyjuvek, an FDA-approved topical gene therapy for dystrophic epidermolysis bullosa skin disease.

Industry overviewAI analysisGenerated by AI from underlying data

Where Biotechnology sits in its cycle right now — and what that implies for $KRYS.

Biotechnology · Healthcare

GLP-1 oral formulation competition — emerging clinical data from pipeline challengers — is the central bifurcation: platform holders (LLY, NVO) defend on efficacy breadth while precision oncology names decouple entirely. FDA catalyst cadence over the next 60 days sets the near-term tone.

What this means for $KRYS

Partial — fee-based midstream revenue has limited direct commodity price exposure but volume ties to upstream production activity.

Top industry ETF

$IBBiShares Biotechnology ETF
+12.1%YTD
+48.9%1Y

Fundamentals & catalyst

Profitability, valuation, and the next earnings event — at a glance, with rule-of-thumb signals.

Key ratios

P/E
39.2How much investors are paying per dollar of profit the company actually earned in the last 12 months. Lower means the stock looks cheaper relative to earnings.~15–25 is typical for the S&P 500; high-growth names trade 30+; hyper-growth or speculative can be 100+ or negative.
ROIC
13.9%What percentage return the business earns on every dollar of capital (equity + debt) deployed in operations. The cleanest measure of business quality.Above ~15% is high-quality; consistently above 25% suggests a real moat. Below the company's cost of capital is value-destroying.
Op margin
42.8%Operating profit (after sales, marketing, R&D, and overhead but before interest and taxes) as a percentage of revenue. The clearest view of how well the underlying business is run.Mature business above 20% is healthy; software businesses can run 30%+; commodity / retail businesses operate in single digits.
FCF yield
2.7%Free cash flow (operating cash flow minus capex) divided by the company's market cap. The cash-on-cash return you'd get owning the whole business at today's price.Above ~5% is attractive; below ~2% means you're paying up for growth. Capital-light businesses (software) run higher than capital-heavy ones (utilities).
P/S
21.3Same idea as P/E but per dollar of revenue. Useful for companies that aren't profitable yet, where P/E is meaningless.Under ~2 is cheap; software / SaaS often runs 8–15; well above 20 implies the market is pricing in very high future growth.
ROE
19.3%Net income as a percentage of shareholders' equity. Similar to ROIC but counts only the equity side.Above 20% is strong, but can be inflated by leverage — a heavily indebted company can show high ROE with weak underlying ROIC.
Gross margin
92.8%Revenue minus the direct cost of producing what was sold, as a percentage of revenue. The first read on whether the product is structurally profitable.Software / SaaS is typically 70%+; consumer goods 30–50%; commodity / hardware businesses can be under 20%.
D/E
0.0Total debt divided by shareholders' equity. Measures how much the business runs on borrowed money versus owner capital.Under 1 is conservative; 1–2 is typical for mature businesses; over 2 is leveraged and more sensitive to interest rates.

Past earnings

QuarterReportedActualEstimateSurprise
Q2 2026Aug 3, 2026$1.79$1.70+5.3%
Q1 2026May 4, 2026$1.83$1.45+26.2%
Q4 2025Feb 17, 2026$1.70$1.62+4.9%
Q3 2025Nov 3, 2025$2.66$1.12+137.5%
Next earningsMon, Nov 2·consensus EPS $1.91

Quarterly trend

QuarterRevenueYoYGrossOpEPSFCF
Q1 FY26$116.4M+31.9%94.6%46.1%$1.91$73.2M
Q4 FY25$107.1M+17.5%89.8%41.5%$1.77$75.4M
Q3 FY25$97.8M+16.6%94.2%42.3%$2.74$38.0M
Q2 FY25$96.0M+36.6%92.5%40.9%$1.33$50.8M

Forward consensus

5-year forecast · up to 6 analysts
FYRevenueRangeEPSRangeAnalysts
FY26$511.6M$504.6M – $518.7M$7.50$6.38 – $8.546
FY27$653.7M$646.8M – $660.5M$9.49$6.80 – $12.466
FY28$849.4M$703.6M – $1.0B$12.36$7.07 – $18.386
FY29$1.3B$1.3B – $1.5B$24.30$22.26 – $27.145
FY30$1.8B$1.6B – $1.9B$33.58$30.76 – $37.503

Setup & momentum

Volume, range, and moving-average position — the technical setup driving short-term moves.

Right now

Vol vs 30dToday's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.0.5×Today's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.
52w rangeWhere the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.91%Where the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.
vs 50d MALatest close vs the 50-day simple moving average. Positive = short-term trend is up.+3.2%Latest close vs the 50-day simple moving average. Positive = short-term trend is up.
vs 200d MALatest close vs the 200-day simple moving average. Positive = long-term trend is up.+25.2%Latest close vs the 200-day simple moving average. Positive = long-term trend is up.

Float & profile

FloatLow float · 23.5M shFree-float shares — the slice of issued stock actually available to trade. Lower buckets squeeze harder on a catalyst.Traded today0.9% of floatToday's volume as a percent of the free float. Above 5% on a single day is unusually high turnover for the available share count.β0.545-year weekly beta vs the S&P 500. Above 1.5 means the stock typically moves more than the index; below 0.8 moves less.

Insider activity

Recent open-market buys and sells by officers and directors — flagged when multiple insiders cluster.

Recent transactions

SellAug 14Dino A RossiDirector25.0K sh$8.2MSellJun 25Thomas John CharlesEVP, General Counsel1.0K sh$347KSellJun 4Suma KrishnanPresident25.0K sh$7.7MSellJun 4Krish S KrishnanCEO25.0K sh$7.7MSellMay 26Thomas John CharlesEVP, General Counsel642 sh$194K
+ 2 other (1 gift · 1 exempt) in window

See when $KRYS insiders are putting their own money in

  • Real-time open-market buys and sells from Form 4 filings
  • Cluster-buy detection when multiple insiders pile in at once
  • 30 / 60 / 180-day windows so you can spot building conviction
Free, forever. No credit card.

SEC filings

Material 8-K, 13D, S-3, and 424B5 events from the last 180 days — the filings that actually move the price.

Recent material filings

8-KShareholder voteMay 208-K — Item 5.07: Shareholder vote
AI summary

Krystal Biotech, Inc. (KRYS) filed an 8-K on May 15, 2026 disclosing annual shareholder meeting vote results (Item 5.07). Krystal Biotech is a Pittsburgh, Pennsylvania-based gene therapy company focused on dermatological conditions listed on Nasdaq. Annual meeting results are routine governance disclosures.

3New insider — initial holdingsMar 63
3New insider — initial holdingsMar 63
+ 11 other (3 13Gs · 2 earnings 8-Ks · 2 10-Qs · 2 proxys) in window

Recent news

Latest headlines from major outlets, sourced and timestamped — context for whatever just moved.

Here Are Friday’s Top Wall Street Analyst Research Calls: Cinemark, Digital Realty, Fox Corporation, Krystal Biotech, LTC Properties, Roku, Sandisk, T-Mobile US, Wayfair, and More247wallst.com·18d agoKrystal Q2 Earnings & Sales Beat Estimates, Pipeline in Focuszacks.com·28d agoKrystal Biotech, Inc. (KRYS) Q2 2026 Earnings Call Transcriptseekingalpha.com·29d agoKrystal Biotech Q2 Earnings Call Highlightsmarketbeat.com·29d agoKrystal Biotech, Inc. (KRYS) Q2 Earnings and Revenues Beat Estimateszacks.com·29d ago

In themes

Explore the broader themes this ticker is being talked about under.

Gene Editing & CRISPR

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TickerTalks is a research tool, not financial advice. We surface social-attention data; we do not make stock recommendations. Past attention is not predictive of future price movements.

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