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TVTVTX

Travere Therapeutics, Inc.

$TVTX·$5.1B·Biotechnology·Healthcare
$55.15+1.9%YTD+41.0%1Y+285.4%
Mentions · last 7 days
2026-06-13: 6 posts2026-06-14: 3 posts2026-06-15: 13 posts2026-06-16: 13 posts2026-06-17: 8 posts2026-06-18: 5 posts2026-06-19: 1 posts500%
Price updated 14h ago·X counts updated 14h ago
TVTVTX
Travere Therapeutics, Inc.$TVTX
$55.15+1.87%50 posts0%
AI analysisFundamentalsVoices on X
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AI verdict & sentimentAI analysisGenerated by AI from underlying data

Today's AI verdict on what's driving $TVTX, plus how loud the X conversation is and which way it's leaning.

AI analysis

TickerTalks’ read on the fundamentals and what’s driving the move.

Proven numbersAcceleratingAI verdict · as of 2026-06-20

The move is getting stronger, with heavier trading behind it.

Travere just licensed civorebrutinib from Everest and has Filspari momentum + long-term DUPLEX data — 285% trailing year for a reason.

Travere Therapeutics is the rare-kidney-disease commercial-stage biotech anchored by Filspari (sparsentan) for IgA nephropathy and FSGS. The June 1 license/collaboration agreement with Everest Medicines for civorebrutinib (EVER001, covalent reversible BTK inhibitor) granting Travere exclusive royalty-bearing rights ex-Asia is a significant pipeline-expansion catalyst. The June 4 long-term Phase 3 DUPLEX study open-label extension data at the 63rd ERA Congress supports the commercial-scaling thesis. Operationally Q1 revenue around $127M grew ~56% year over year, gross margin near 79%, operating margin still negative at -29%, free cash flow at -$63M for the quarter, EPS at -$0.39 vs -$0.30 consensus. Sell-side modeling has FY26 revenue near $697M with EPS at $0.18 (just turning positive), stepping to $967M and $2.43 in FY27, then $1.18B and $3.46 in FY28. The stock is up about 41% YTD and ~285% over the trailing year, sits 26% above the 50-day and 64% above the 200-day, and is at the top 2% of its 52-week range. The June 16 CRO Rote retirement announcement (effective Feb 2027) is orderly succession planning. Insider activity is M-Exempt + S-Sale combos (Baynes 9K + $225K, Coughlin 20K + $501K) — within ordinary pattern. What sustains the trajectory is Filspari prescription growth holding into 2H, civorebrutinib clinical milestones advancing, and Q2 EPS clearing -$0.085 consensus; what would invalidate it is a Filspari label-restriction event or a Phase-3 pipeline setback.

What to watch: Filspari prescription growth, civorebrutinib clinical milestones, CRO succession planning, Q2 EPS against -$0.085 consensus, and DUPLEX long-term safety data.

On the calendar: Q2 2026 earnings on 2026-08-05.

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What it does

Plain-English summary of the business — what they sell and how they make money.

Travere Therapeutics, Inc., a biopharmaceutical firm headquartered in San Diego, California, was founded in 2008 with a mission to discover, develop, commercialize, and deliver treatments for rare diseases. The company adopted its current name in November 2020, previously operating as Retrophin, Inc. Its current product offerings include Chenodal, an orally administered synthetic form of chenodeoxycholic acid, used to dissolve radiolucent gallstones. Another key product is Cholbam, a cholic acid capsule prescribed for both children and adults suffering from bile acid synthesis disorders stemming from single enzyme defects, and as an auxiliary treatment for peroxisomal disorders. Additionally, Thiola and Thiola EC, tiopronin tablets, are available for managing homozygous cystinuria. In its development pipeline, Travere is advancing several therapeutic candidates. Sparsentan is currently in Phase III clinical trials, being investigated for the treatment of focal segmental glomerulosclerosis and immunoglobulin A nephropathy. Also under development is TVT-058, a pioneering investigational human enzyme replacement candidate, which is undergoing Phase I/II clinical trials for classical homocystinuria. The company actively engages in strategic partnerships, holding a cooperative research and development agreement with the National Institutes of Health's National Center for Advancing Translational Sciences. It also collaborates with patient advocacy groups such as CDG Care and the Alagille Syndrome Alliance, collectively working towards identifying potential small molecule therapies for NGLY1 deficiency and Alagille syndrome.

Industry overviewAI analysisGenerated by AI from underlying data

Where Biotechnology sits in its cycle right now — and what that implies for $TVTX.

Biotechnology · Healthcare

GLP-1 obesity pipeline competition is the dominant structural driver — the 'next phase' of obesity drugs (oral formulations, differentiated mechanisms) is reshaping clinical bets for NVO competitors. Gene editing (CRSP, BEAM, NTLA, PRME) is transitioning from clinical to commercial-maturation phase with Casgevy scaling; oncology binary events (IBRX, ALLO, KURA) define the near-term calendar.

Top industry ETF

$IBBiShares Biotechnology ETF
+2.4%YTD
+38.3%1Y

Fundamentals & catalyst

Profitability, valuation, and the next earnings event — at a glance, with rule-of-thumb signals.

Key ratios

P/E
-236.5How much investors are paying per dollar of profit the company actually earned in the last 12 months. Lower means the stock looks cheaper relative to earnings.~15–25 is typical for the S&P 500; high-growth names trade 30+; hyper-growth or speculative can be 100+ or negative.
ROIC
-13.1%What percentage return the business earns on every dollar of capital (equity + debt) deployed in operations. The cleanest measure of business quality.Above ~15% is high-quality; consistently above 25% suggests a real moat. Below the company's cost of capital is value-destroying.
Op margin
-10.6%Operating profit (after sales, marketing, R&D, and overhead but before interest and taxes) as a percentage of revenue. The clearest view of how well the underlying business is run.Mature business above 20% is healthy; software businesses can run 30%+; commodity / retail businesses operate in single digits.
FCF yield
0.3%Free cash flow (operating cash flow minus capex) divided by the company's market cap. The cash-on-cash return you'd get owning the whole business at today's price.Above ~5% is attractive; below ~2% means you're paying up for growth. Capital-light businesses (software) run higher than capital-heavy ones (utilities).
P/S
9.6Same idea as P/E but per dollar of revenue. Useful for companies that aren't profitable yet, where P/E is meaningless.Under ~2 is cheap; software / SaaS often runs 8–15; well above 20 implies the market is pricing in very high future growth.
ROE
-26.8%Net income as a percentage of shareholders' equity. Similar to ROIC but counts only the equity side.Above 20% is strong, but can be inflated by leverage — a heavily indebted company can show high ROE with weak underlying ROIC.
Gross margin
94.0%Revenue minus the direct cost of producing what was sold, as a percentage of revenue. The first read on whether the product is structurally profitable.Software / SaaS is typically 70%+; consumer goods 30–50%; commodity / hardware businesses can be under 20%.
D/E
3.3Total debt divided by shareholders' equity. Measures how much the business runs on borrowed money versus owner capital.Under 1 is conservative; 1–2 is typical for mature businesses; over 2 is leveraged and more sensitive to interest rates.

Past earnings

QuarterReportedActualEstimateSurprise
Q1 2026May 4, 2026$-0.39$-0.30-30.0%
Q4 2025Feb 19, 2026$0.03$0.030.0%
Q3 2025Oct 30, 2025$0.28$-0.31+190.3%
Q2 2025Aug 6, 2025$-0.14$-0.28+50.0%
Next earningsWed, Aug 5·consensus EPS $-0.08

Quarterly trend

QuarterRevenueYoYGrossOpEPSFCF
Q1 FY26$127.2M+55.6%79.0%-29.0%$-0.40$-62.5M
Q4 FY25$129.7M+73.4%98.0%-25.0%$-0.24$61.1M
Q3 FY25$164.9M+162.1%99.0%15.1%$0.29$14.2M
Q2 FY25$114.4M+111.5%98.7%-11.1%$-0.14$4.7M

Forward consensus

5-year forecast · up to 11 analysts
FYRevenueRangeEPSRangeAnalysts
FY26$696.7M$650.1M – $743.8M$0.18-$0.28 – $0.7411
FY27$967.1M$922.2M – $1.1B$2.43-$0.31 – $7.1811
FY28$1.2B$1.2B – $1.2B$3.46$2.37 – $5.989
FY29$1.5B$1.3B – $1.8B$4.46$3.69 – $5.614
FY30$1.8B$1.5B – $2.1B$5.55$4.59 – $6.994

Setup & momentum

Volume, range, and moving-average position — the technical setup driving short-term moves.

Right now

Vol vs 30dToday's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.2.8×Today's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.
52w rangeWhere the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.98%Where the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.
vs 50d MALatest close vs the 50-day simple moving average. Positive = short-term trend is up.+25.9%Latest close vs the 50-day simple moving average. Positive = short-term trend is up.
vs 200d MALatest close vs the 200-day simple moving average. Positive = long-term trend is up.+64.1%Latest close vs the 200-day simple moving average. Positive = long-term trend is up.

Float & profile

FloatMid float · 90.4M shFree-float shares — the slice of issued stock actually available to trade. Lower buckets squeeze harder on a catalyst.Traded today7.3% of floatToday's volume as a percent of the free float. Above 5% on a single day is unusually high turnover for the available share count.β1.145-year weekly beta vs the S&P 500. Above 1.5 means the stock typically moves more than the index; below 0.8 moves less.FilingActive offeringA shelf registration (S-3 / S-3ASR / S-1) or prospectus supplement (424B*) was filed in the last 90 days — the company is registered to (or actively) issuing new shares. Dilution risk.

Insider activity

Recent open-market buys and sells by officers and directors — flagged when multiple insiders cluster.

Recent transactions

SellJun 12Timothy CoughlinDirector10.0K sh$501KSellJun 12Roy D. BaynesDirector4.5K sh$225KSellMay 15Timothy CoughlinDirector3.3K sh$141KSellMay 6William E. RoteChief Research Officer2.8K sh$121KSellMay 6Elizabeth E ReedChief Legal Officer and GC2.1K sh$91KSellMay 6Jula InrigCHIEF MEDICAL OFFICER311 sh$14KSellMay 5Roy D. BaynesDirector4.5K sh$210KSellMay 5Elizabeth E ReedChief Legal Officer and GC2.2K sh$101KSellMay 5Jula InrigCHIEF MEDICAL OFFICER2.2K sh$101KSellMay 4Jeffrey A MecklerDirector8.0K sh$360K
1–10 of 12
+ 19 other (12 awards · 7 exempts) in window

See when $TVTX insiders are putting their own money in

  • Real-time open-market buys and sells from Form 4 filings
  • Cluster-buy detection when multiple insiders pile in at once
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SEC filings

Material 8-K, 13D, S-3, and 424B5 events from the last 180 days — the filings that actually move the price.

Recent material filings

8-KOfficer or director changeJun 168-K — Item 5.02: Officer or director change
AI summary

Travere Therapeutics Chief Research Officer William Rote, Ph.D. provided notice on June 12, 2026 of his retirement effective February 17, 2027, the 10-year anniversary of his employment; he will remain in his current role and assist with transition through the Retirement Date. No successor CRO is named in the excerpt. Orderly planned departure with 8+ months of notice; the lengthy notice period suggests internal succession planning is underway, though the CRO role is material for a company mid-development on civorebrutinib and other pipeline assets.

8-KMaterial agreementJun 28-K — Item 1.01: Material agreement
AI summary

Travere Therapeutics entered a license and collaboration agreement with Everest Medicines (Singapore) Pte. Ltd. on June 1, 2026 under which Everest grants Travere exclusive, royalty-bearing rights to develop and commercialize civorebrutinib (EVER001), a covalent reversible BTK inhibitor, in all fields across all countries outside China and certain East/Southeast Asian territories. Travere gains rights to make, import, distribute, sell, and develop the compound globally ex-Asia, with rights including a sublicense to third-party IP. Financial terms (upfront, milestones, royalties) are not disclosed in the excerpt. Material in-licensing deal — civorebrutinib adds a BTK inhibitor to Travere's pipeline, complementing its rare kidney disease focus, likely funded by the concurrent $525M convertible note raise.

8-KOfficer or director changeMay 218-K — Item 5.02: Officer or director change · Item 5.07: Shareholder vote
AI summary

Travere Therapeutics held its 2026 Annual Meeting at which stockholders approved an amendment to the 2018 Equity Incentive Plan increasing the authorized share pool by 3,000,000 shares; this is disclosed under Item 5.02 as a compensatory arrangement approval. Item 5.07 covers the broader Annual Meeting voting results. Additional annual meeting proposals beyond the equity plan are described in the proxy but their vote outcomes are not fully detailed in the excerpt. The 3M share addition provides equity compensation runway; mildly dilutive.

8-KMaterial agreementMay 118-K — Item 1.01: Material agreement · Item 2.03: Material debt obligation · Item 3.02: Unregistered equity sale · Item 8.01: Other event
AI summary

Travere Therapeutics completed a $525 million registered underwritten offering of 0.50% Convertible Senior Notes due May 15, 2032 on May 11, 2026, including $50M from full exercise of the underwriters' overallotment (underwriters: J.P. Morgan, Jefferies, Leerink Partners). Notes are redeemable at Travere's option from May 21, 2029 onward if the stock exceeds 130% of the conversion price; settlement in cash, shares, or a combination. Items 2.03/3.02 cover the debt creation and private placement aspects; Item 8.01 likely covers a concurrent capped call transaction to limit dilution above the conversion premium. A large-scale capital raise at low cost of debt — the $525M will fund pipeline development including the Everest BTK inhibitor license and commercial FILSPARI activities.

424B5Prospectus supplement (offering)May 7424B5
AI summary

Travere Therapeutics filed a 424B5 prospectus supplement for $475 million of 0.50% Convertible Senior Notes due May 15, 2032 at 100% issue price (with $50M underwriter greenshoe option). Conversion is permitted under specified stock price and trading triggers; notes are redeemable from May 21, 2029 onward if the stock exceeds 130% of the conversion price; settlement in cash, shares, or a combination at Travere's option. This is the pricing prospectus for the convertible offering, which was ultimately upsized to $525M following full exercise of the overallotment (see Job 45). The offering provides long-term capital at a low 0.50% coupon with dilution contingent on stock performance above the conversion premium.

424B5Prospectus supplement (offering)May 5424B5
AI summary

Travere Therapeutics filed an earlier 424B5 prospectus supplement for $400 million (with $60M greenshoe option) of convertible senior notes due 2032; the coupon and conversion price fields appear as blank placeholders in the excerpt, indicating this was a preliminary or term-pending filing before pricing was finalized. This preliminary prospectus was superseded by the final $475M pricing prospectus (Job 49) and the ultimately closed $525M offering (Job 45). Administrative/preliminary filing for Travere's convertible note offering process.

+ 20 other (8 13Gs · 3 earnings 8-Ks · 2 routine 8-Ks · 2 proxys) in window

Recent news

Latest headlines from major outlets, sourced and timestamped — context for whatever just moved.

Travere Therapeutics Announces Planned Retirement of Chief Research Officer in 2027businesswire.com·4d agoTravere Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)businesswire.com·9d agoTravere Therapeutics, Inc. (TVTX) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcriptseekingalpha.com·12d agoTravere Therapeutics Presents Long-Term Open-Label Extension Data from the Phase 3 DUPLEX Study at the 63rd European Renal Association (ERA) 2026 Congressbusinesswire.com·16d agoEverest Medicines Enters into Exclusive Licensing Agreement with Travere Therapeutics for Civorebrutinib a Potential Best-in-Class BTK Inhibitor for Rare Kidney Diseases, Driving Value Conversiongurufocus.com·17d ago

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