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QTQTTB

Q32 Bio Inc.

$QTTB·$167M·Biotechnology·Healthcare
$15.05-1.1%YTD+360.9%1Y+447.1%
Mentions · last 7 days
2026-07-10: 51 posts2026-07-11: 17 posts2026-07-12: 34 posts2026-07-13: 1,892 posts2026-07-14: 930 posts2026-07-15: 95 posts2026-07-16: 46 posts3,065+46%
Price updated 7m ago·X counts updated 22h ago
QTQTTB
$QTTBQ32 Bio Inc.
$15.05-1.05%3.1k posts+46%
AI analysisFundamentalsVoices on X
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AI verdict & sentimentAI analysisGenerated by AI from underlying data

Today's AI verdict on what's driving $QTTB, plus how loud the X conversation is and which way it's leaning.

AI analysis

TickerTalks’ read on the fundamentals and what’s driving the move.

Hinges on a big eventCooling offAI verdict · as of 2026-07-17

Catching its breath after a run — could pick back up or fade from here.

Immunology micro-cap just delivered the alopecia data everyone wanted and then diluted 30% into the print.

Q32 Bio is a clinical-stage immunology company whose lead asset — bempikibart, an anti-IL-2Rα antibody — targets severe alopecia areata and, longer term, other autoimmune indications. This week has been the crescendo the whole thesis was built around.

What just happened:

  • The data was strong enough to move the stock: Phase 2 Part B efficacy results in severe alopecia areata (SALT 50-100 patients) landed on July 13 and prior-week trials were called 'Strong Buy' by Seeking Alpha — this is the datapoint the +447% one-year run was betting on.
  • The company monetized the reaction immediately: a $200M public offering priced July 15 at $18.25 with 10.96M shares plus 4.93M pre-funded warrants — call it ~30% dilution, but it also refills the trials budget through the next set of readouts.
  • The insider signal was consistent, not scary: director Isaac Manke's $299K exercise-and-hold is the only recent Form 4 — no cluster of officer selling into the news, which matters for a $200M-market-cap biotech.
  • The setup is the classic post-catalyst coil: shares at 62% of the 52-week range and above the 200-day moving average by 169%, with the deal-priced $18.25 as the immediate reference — expect chop until the follow-on readouts land.

The forward look: the story is now about what comes after alopecia — atopic dermatitis, additional dosing cohorts, and the pipeline. What extends the move: any incremental data cut on bempikibart that supports labeling toward moderate patients (a much larger commercial market). What breaks it: a soft August 5 quarterly update, a partnership discussion that fizzles, or fresh dilution that signals cash is tighter than the market believes.

Agrees with X sentimentThe (older, June 8) X read framing this as a small-cap immunology winner riding insider buys is directionally right — the Phase 2 data has since validated the setup. The crowd's missing piece: the $200M raise materially reset the dilution math, which is the near-term overhang.

What to watch: The August 5 Q2 update for cash runway and any partnership/licensing hint, plus the next bempikibart data cut in a broader alopecia or atopic-dermatitis population; a fizzled follow-on readout or a second raise near-term would end the coil down, not up.

On the calendar: 2026-08-05 — Q2 2026 earnings and pipeline update

X sentiment

What the X crowd is saying right now — descriptive, summarised from the day’s posts.

Bullish sentiment10 posts analyzed · as of 2026-06-08

Q32 Bio is being framed as a small-cap immunology winner: holders sitting on 300% gains, $30M of insider buys at $8 by multiple directors (largest insider buys in the past week), and bulls explicitly frame QTTB as the recovery name for ABVX losses. The bear voice is essentially absent.

Read the AI verdict + X sentiment for $QTTB

  • One-line verdict on what's driving the move — fundamentals, momentum, both, or an event
  • Next dated catalyst when there is one (earnings, deal closing, activist clock)
  • X crowd read with bullish/bearish call + post volume
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What it does

Plain-English summary of the business — what they sell and how they make money.

Clinical-stage autoimmune biotech with ADX-097, a complement inhibitor targeting inflammatory kidney and skin diseases.

Industry overviewAI analysisGenerated by AI from underlying data

Where Biotechnology sits in its cycle right now — and what that implies for $QTTB.

Biotechnology · Healthcare

No material change from last week — ADA conference oral formulation competition is bifurcating biotech multiples between GLP-1 platform holders and precision oncology innovators.

What this means for $QTTB

Partial — Clinical-stage autoimmune biotech with ADX-097, a complement inhibitor targeting inflammatory kidney and skin diseases; the GLP-1 pipeline bifurcation and ADA oral formulation competition is a secondary rather than primary near-term earnings catalyst.

Top industry ETF

$IBBiShares Biotechnology ETF
+11.7%YTD
+44.5%1Y

Fundamentals & catalyst

Profitability, valuation, and the next earnings event — at a glance, with rule-of-thumb signals.

Key ratios

P/E
5.6How much investors are paying per dollar of profit the company actually earned in the last 12 months. Lower means the stock looks cheaper relative to earnings.~15–25 is typical for the S&P 500; high-growth names trade 30+; hyper-growth or speculative can be 100+ or negative.
ROIC
36.1%What percentage return the business earns on every dollar of capital (equity + debt) deployed in operations. The cleanest measure of business quality.Above ~15% is high-quality; consistently above 25% suggests a real moat. Below the company's cost of capital is value-destroying.
Op margin
39.8%Operating profit (after sales, marketing, R&D, and overhead but before interest and taxes) as a percentage of revenue. The clearest view of how well the underlying business is run.Mature business above 20% is healthy; software businesses can run 30%+; commodity / retail businesses operate in single digits.
FCF yield
-16.4%Free cash flow (operating cash flow minus capex) divided by the company's market cap. The cash-on-cash return you'd get owning the whole business at today's price.Above ~5% is attractive; below ~2% means you're paying up for growth. Capital-light businesses (software) run higher than capital-heavy ones (utilities).
P/S
3.1Same idea as P/E but per dollar of revenue. Useful for companies that aren't profitable yet, where P/E is meaningless.Under ~2 is cheap; software / SaaS often runs 8–15; well above 20 implies the market is pricing in very high future growth.
ROE
231%Net income as a percentage of shareholders' equity. Similar to ROIC but counts only the equity side.Above 20% is strong, but can be inflated by leverage — a heavily indebted company can show high ROE with weak underlying ROIC.
Gross margin
99.5%Revenue minus the direct cost of producing what was sold, as a percentage of revenue. The first read on whether the product is structurally profitable.Software / SaaS is typically 70%+; consumer goods 30–50%; commodity / hardware businesses can be under 20%.
D/E
0.2Total debt divided by shareholders' equity. Measures how much the business runs on borrowed money versus owner capital.Under 1 is conservative; 1–2 is typical for mature businesses; over 2 is leveraged and more sensitive to interest rates.

Past earnings

QuarterReportedActualEstimateSurprise
Q1 2026May 5, 2026$-0.54$-0.68+20.6%
Q4 2025Mar 10, 2026$3.65$-0.85+529.4%
Q3 2025Nov 13, 2025$-0.60$-1.39+56.8%
Q2 2025Aug 6, 2025$-0.78$-1.14+31.6%
Next earningsWed, Aug 5·consensus EPS $-0.53

Quarterly trend

QuarterRevenueYoYGrossOpEPSFCF
Q1 FY26$0———$-0.54$-6.3M
Q4 FY25$53.7M—99.8%85.4%$4.60$-6.2M
Q3 FY25$0———$-0.60$-4.2M
Q2 FY25$0———$-0.78$-10.7M

Forward consensus

5-year forecast · up to 5 analysts
FYRevenueRangeEPSRangeAnalysts
FY26$1.3M$1.3M – $1.3M-$1.82-$2.04 – -$1.645
FY27$1.3M$1.3M – $1.3M-$2.23-$2.39 – -$1.975
FY28$3.3M$3.3M – $3.3M-$2.09-$2.97 – -$1.525
FY29$45.7M$45.7M – $45.7M-$1.61-$1.61 – -$1.612
FY30$154.9M$154.9M – $154.9M-$0.81-$0.81 – -$0.812

Setup & momentum

Volume, range, and moving-average position — the technical setup driving short-term moves.

Right now

Vol vs 30dToday's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.1.3×Today's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.
52w rangeWhere the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.62%Where the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.
vs 50d MALatest close vs the 50-day simple moving average. Positive = short-term trend is up.+43.5%Latest close vs the 50-day simple moving average. Positive = short-term trend is up.
vs 200d MALatest close vs the 200-day simple moving average. Positive = long-term trend is up.+168.8%Latest close vs the 200-day simple moving average. Positive = long-term trend is up.

Float & profile

FilingActive offeringA shelf registration (S-3 / S-3ASR / S-1) or prospectus supplement (424B*) was filed in the last 90 days — the company is registered to (or actively) issuing new shares. Dilution risk.

Insider activity

Recent open-market buys and sells by officers and directors — flagged when multiple insiders cluster.

Recent transactions

BuyMay 28Diyong XuDirector1.9M sh$15.0MBuyMay 28Orbimed Advisors LlcDirector1.9M sh$15.0MSellFeb 25Lee KalowskiCFO4.0K sh$18KSellFeb 25Shelia M. VioletteChief Scientific Officer2.8K sh$13KSellFeb 25Morrison Jodie PopeCEO9.9K sh$45K
+ 12 other (11 awards · 1 exempt) in window

See when $QTTB insiders are putting their own money in

  • Real-time open-market buys and sells from Form 4 filings
  • Cluster-buy detection when multiple insiders pile in at once
  • 30 / 60 / 180-day windows so you can spot building conviction
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SEC filings

Material 8-K, 13D, S-3, and 424B5 events from the last 180 days — the filings that actually move the price.

Recent material filings

8-KMaterial agreementJul 158-K — Item 1.01: Material agreement
AI summary

Q32 Bio (QTTB) entered into an underwriting agreement for a public offering of 10,958,904 shares of common stock at $18.25 per share, plus pre-funded warrants to purchase 4,931,506 shares at $18.2499 per warrant, on July 15, 2026. The underwriters have a 30-day option to purchase up to 1,643,835 additional shares. Estimated net proceeds are approximately $187.6 million ($215.8 million if the overallotment is exercised in full), intended for working capital and research and development. Closing was expected on approximately July 16, 2026.

424B5Prospectus supplement (offering)Jul 15424B5
AI summary

Q32 Bio (QTTB) filed a 424B5 prospectus supplement on July 14, 2026, for a public offering of 10,958,904 shares of common stock at $18.25 per share plus 4,931,506 pre-funded warrants at $18.2499 each, with an overallotment option for up to 1,643,835 additional shares. Joint book-running managers are Morgan Stanley, Jefferies, Cantor Fitzgerald, and Oppenheimer & Co.; H.C. Wainwright & Co. is lead manager. Estimated net proceeds are approximately $187.6 million. Proceeds are intended for working capital and R&D activities.

424B5Prospectus supplement (offering)Jul 13424B5
AI summary

Q32 Bio (QTTB) filed a preliminary 424B5 prospectus supplement on July 13, 2026, for a proposed registered public offering of common stock and pre-funded warrants. Joint book-running managers include Morgan Stanley, Jefferies, Cantor Fitzgerald, and Oppenheimer & Co., with H.C. Wainwright & Co. as lead manager. Offering price and final share count were not yet determined at the time of this preliminary filing. This is the earlier of two 424B5 filings for the same Q32 Bio offering.

8-KPress release / Reg FDJul 138-K — Item 7.01: Press release / Reg FD · Item 8.01: Other event
AI summary

Q32 Bio (QTTB) disclosed Phase 2 Part B efficacy data for bempikibart (anti-IL-2Rα antibody) in severe alopecia areata (AA) on July 13, 2026. The study enrolled 33 patients with SALT scores of 50–100 and episode durations of four years or less, of whom 36.4% had prior JAK inhibitor exposure. Treatment consisted of a 200 mg loading dose administered weekly for four weeks followed by a maintenance regimen, continued through 36 weeks. Enrollment exceeded the initial target due to patient demand, and the blinded, sham-controlled study design provides robust evidence for the bempikibart program.

S-3Shelf registrationJun 25S-3
AI summary

Q32 Bio Inc. filed an S-3 shelf registration statement on June 25, 2026, establishing a framework to sell securities on a delayed or continuous basis under Rule 415. The filing registers unspecified types and amounts of securities. CEO Jodie Morrison is listed as the agent contact. This is a standard shelf registration enabling future capital raises — no specific offering size or timing is determined yet. Administrative capital markets infrastructure; not an immediate dilutive event.

8-KShareholder voteJun 168-K — Item 5.07: Shareholder vote
AI summary

QTTB filed an 8-K Item 5.07 on June 16, 2026 reporting submission of matters to a vote of security holders (annual meeting results). Body unavailable — excerpt contains insufficient narrative to extract specific vote tallies or proposal outcomes.

3New insider — initial holdingsJun 83
AI summary

Atlas Venture Opportunity Fund III, L.P. (via general partners Atlas Venture Associates Opportunity III, L.P. and LLC) filed a Form 3 for Q32 Bio Inc. (QTTB), reporting initial beneficial ownership as part of an Atlas Venture group that collectively holds greater than 10% of outstanding common stock. The exact share count held directly by AVOF III is not stated in this excerpt. Routine Form 3 for institutional 10%+ holder group — signals Atlas remains a major backer of QTTB.

SC 13D/AActivist amendmentJun 1SC 13D/A
AI summary

An institutional investor filed Amendment No. 3 to its Schedule 13D on Q32 Bio (QTTB); exact share count and ownership percentage not visible in excerpt. Routine beneficial ownership update by an existing 5%+ holder.

+ 30 other (10 13Gs · 3 SC 13D/As · 3 8-Ks · 3 424B5s) in window

Recent news

Latest headlines from major outlets, sourced and timestamped — context for whatever just moved.

Wall Street Analysts See an 80.12% Upside in Q32 Bio (QTTB): Can the Stock Really Move This High?zacks.com·2d agoQ32 Bio Announces Pricing of $200 Million Public Offering of Common Stock and Pre-Funded Warrantsprnewswire.com·3d agoWhy Q32 Bio Stock Skyrocketed Todayfool.com·4d agoQ32 Bio: 'Strong Buy' On Solid Bempikibart SIGNAL-AA Study Data And Catalystsseekingalpha.com·4d agoQ32 Bio Announces Proposed Public Offering of Common Stock and Pre-Funded Warrantsprnewswire.com·4d ago

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Voices on X · last 7 days

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