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MIMIRM

Mirum Pharmaceuticals, Inc.

$MIRM·$6.5B·Biotechnology·Healthcare
$104.33-0.2%YTD+31.9%1Y+99.7%
Mentions · last 7 days
2026-07-28: 0 posts2026-07-29: 3 posts2026-07-30: 3 posts2026-07-31: 15 posts2026-08-01: 1 posts2026-08-02: 6 posts2026-08-03: 9 posts37+27%
Price updated 4h ago·X counts updated 1d ago
MIMIRM
$MIRMMirum Pharmaceuticals, Inc.
$104.33-0.25%37 posts+27%
AI analysisFundamentalsVoices on X
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AI verdict & sentimentAI analysisGenerated by AI from underlying data

Top X posts

Today's AI verdict on what's driving $MIRM, plus how loud the X conversation is and which way it's leaning.

AI analysis

TickerTalks’ read on the fundamentals and what’s driving the move.

Proven numbersAcceleratingAI verdict · as of 2026-08-04

The move is getting stronger, with heavier trading behind it.

Mirum Pharmaceuticals up 100% T12M on liver-disease franchise expansion — Aug 5 earnings with insider selling as the mild offset.

Mirum Pharmaceuticals is a rare-disease biotech focused on liver disease (Livmarli for cholestatic pruritus, plus expanding portfolio). It's up 100% T12M after a July portfolio broadening announcement, and Aug 5 earnings tests the commercial-ramp thesis against a July insider sale cluster.

  • The July 4 portfolio broadening is the story-defining event: 'Liver Disease Juggernaut Just Broadened Its Portfolio' per Seeking Alpha — real franchise expansion, and Livmarli commercial ramp is now supplemented by additional pipeline candidates.
  • Q1 was a step-change: revenue grew 43% YoY to $160M with 82% GM and -12% OM (with -$13.43 EPS reflecting a one-time charge) — real Livmarli commercial acceleration, and 82% GM confirms pricing power.
  • The July 6 insider distribution is worth naming but option-driven: Bjerkholt sold 5,000 at $122 (~$611K) and Peetz exercised 40K options at $2.94 and sold 20K at $122 (~$2.45M) — cashless-exercise distribution, not fundamentally negative.
  • The June 25 biotech ETF rebalance surge is a real cohort tailwind: biotech ETF +10% post-rebalance — real cohort-flow signal, and MIRM's basket inclusion provides incremental passive support.

Aug 5 is the tension breaker. Q2 with continued 40%+ growth plus pipeline expansion commentary and any FY guidance raise restarts the compounding toward $130; a soft Livmarli script commentary or further insider distribution and the setup pauses with $80 as support with the -12% Q1 OM as the specific downside risk.

What to watch: Aug 5 Q2 print: watch for Livmarli script trajectory, pipeline expansion commentary, OM cadence toward breakeven, FY guidance revision, and any post-print insider follow-through — the sustain signals for the +100% T12M run.

On the calendar: 2026-08-05 — Q2 earnings

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What it does

Plain-English summary of the business — what they sell and how they make money.

Rare liver disease biotech with approved LIVMARLI for pediatric PFIC and Alagille syndrome; Volixibat in late-stage trials.

Industry overviewAI analysisGenerated by AI from underlying data

Where Biotechnology sits in its cycle right now — and what that implies for $MIRM.

Biotechnology · Healthcare

No material change from last week — ADA conference oral formulation competition is bifurcating biotech multiples between GLP-1 platform holders and precision oncology innovators.

What this means for $MIRM

Neutral — Rare liver disease biotech with approved LIVMARLI for pediatric PFIC and Alagille syndrome; Volixibat in late-stage trials; limited read-through from biotechnology macro dynamics to this specific revenue mix.

Top industry ETF

$IBBiShares Biotechnology ETF
+12.1%YTD
+40.5%1Y

Fundamentals & catalyst

Profitability, valuation, and the next earnings event — at a glance, with rule-of-thumb signals.

Key ratios

P/E
-7.9How much investors are paying per dollar of profit the company actually earned in the last 12 months. Lower means the stock looks cheaper relative to earnings.~15–25 is typical for the S&P 500; high-growth names trade 30+; hyper-growth or speculative can be 100+ or negative.
ROIC
-11.3%What percentage return the business earns on every dollar of capital (equity + debt) deployed in operations. The cleanest measure of business quality.Above ~15% is high-quality; consistently above 25% suggests a real moat. Below the company's cost of capital is value-destroying.
Op margin
-12.3%Operating profit (after sales, marketing, R&D, and overhead but before interest and taxes) as a percentage of revenue. The clearest view of how well the underlying business is run.Mature business above 20% is healthy; software businesses can run 30%+; commodity / retail businesses operate in single digits.
FCF yield
-3.2%Free cash flow (operating cash flow minus capex) divided by the company's market cap. The cash-on-cash return you'd get owning the whole business at today's price.Above ~5% is attractive; below ~2% means you're paying up for growth. Capital-light businesses (software) run higher than capital-heavy ones (utilities).
P/S
9.4Same idea as P/E but per dollar of revenue. Useful for companies that aren't profitable yet, where P/E is meaningless.Under ~2 is cheap; software / SaaS often runs 8–15; well above 20 implies the market is pricing in very high future growth.
ROE
-289%Net income as a percentage of shareholders' equity. Similar to ROIC but counts only the equity side.Above 20% is strong, but can be inflated by leverage — a heavily indebted company can show high ROE with weak underlying ROIC.
Gross margin
81.4%Revenue minus the direct cost of producing what was sold, as a percentage of revenue. The first read on whether the product is structurally profitable.Software / SaaS is typically 70%+; consumer goods 30–50%; commodity / hardware businesses can be under 20%.
D/E
1.3Total debt divided by shareholders' equity. Measures how much the business runs on borrowed money versus owner capital.Under 1 is conservative; 1–2 is typical for mature businesses; over 2 is leveraged and more sensitive to interest rates.

Past earnings

QuarterReportedActualEstimateSurprise
Q1 2026May 6, 2026$-13.43$-0.40-3257.5%
Q4 2025Feb 25, 2026$-0.11$0.02-650.0%
Q3 2025Nov 4, 2025$0.05$-0.10+150.0%
Q2 2025Aug 6, 2025$-0.12$-0.31+61.3%
Next earningsWed, Aug 5·consensus EPS $-0.74

Quarterly trend

QuarterRevenueYoYGrossOpEPSFCF
Q1 FY26$159.9M+43.3%81.9%-39.5%$-13.43$-229.4M
Q4 FY25$148.9M+49.8%81.0%-3.1%$-0.12$5.5M
Q3 FY25$133.0M+47.2%80.8%2.0%$0.06$39.5M
Q2 FY25$127.8M+64.1%81.7%-3.9%$-0.12$11.9M

Forward consensus

5-year forecast · up to 9 analysts
FYRevenueRangeEPSRangeAnalysts
FY26$674.5M$669.5M – $683.7M-$15.63-$17.47 – -$14.249
FY27$812.6M$751.5M – $845.3M-$0.66-$13.86 – $5.499
FY28$1.1B$944.4M – $1.2B$2.38$0.63 – $5.709
FY29$1.4B$1.3B – $1.5B$5.54$5.02 – $6.064
FY30$1.7B$1.6B – $1.9B$8.86$8.02 – $9.694

Setup & momentum

Volume, range, and moving-average position — the technical setup driving short-term moves.

Right now

Vol vs 30dToday's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.0.6×Today's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.
52w rangeWhere the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.68%Where the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.
vs 50d MALatest close vs the 50-day simple moving average. Positive = short-term trend is up.-4.5%Latest close vs the 50-day simple moving average. Positive = short-term trend is up.
vs 200d MALatest close vs the 200-day simple moving average. Positive = long-term trend is up.+12.9%Latest close vs the 200-day simple moving average. Positive = long-term trend is up.

Float & profile

FloatMid float · 52.5M shFree-float shares — the slice of issued stock actually available to trade. Lower buckets squeeze harder on a catalyst.Traded today1.0% of floatToday's volume as a percent of the free float. Above 5% on a single day is unusually high turnover for the available share count.β0.485-year weekly beta vs the S&P 500. Above 1.5 means the stock typically moves more than the index; below 0.8 moves less.

Insider activity

Recent open-market buys and sells by officers and directors — flagged when multiple insiders cluster.

Recent transactions

SellJul 6Christopher PeetzCEO20.0K sh$2.4MSellJul 6Eric BjerkholtCFO5.0K sh$611KSellJul 1Jolanda HoweSVP, GLOBAL CONTROLLER2.7K sh$327KSellJun 17Jolanda HoweSVP, GLOBAL CONTROLLER2.6K sh$264KSellJun 8Eric BjerkholtCFO5.0K sh$469KSellJun 1Christopher PeetzCEO30.0K sh$2.9MSellJun 1Saira RamasastryDirector4.0K sh$398KSellMay 15Saira RamasastryDirector2.0K sh$219KSellApr 15Saira RamasastryDirector2.0K sh$194KSellMar 16Eric BjerkholtCFO7.3K sh$670K
+ 19 other (11 exempts · 8 awards) in window

See when $MIRM insiders are putting their own money in

  • Real-time open-market buys and sells from Form 4 filings
  • Cluster-buy detection when multiple insiders pile in at once
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SEC filings

Material 8-K, 13D, S-3, and 424B5 events from the last 180 days — the filings that actually move the price.

Recent material filings

8-KShareholder voteJun 188-K — Item 5.07: Shareholder vote
AI summary

Mirum Pharmaceuticals held its 2026 Annual Meeting on June 15, 2026, with 60.98M shares outstanding as of the April 20 record date. Stockholders elected three Class I directors (Lon Cardon, William Fairey, Timothy Walbert) for three-year terms through 2029; Walbert received notably elevated withhold votes (14.1M vs. ~1.9M for Cardon/Fairey), a potential advisory-firm flag. Ernst & Young LLP was ratified as auditor and executive compensation was approved on an advisory basis. Routine annual meeting; the director vote split on Walbert is the only non-standard outcome.

8-KMaterial agreementMay 188-K — Item 1.01: Material agreement · Item 2.03: Material debt obligation · Item 3.02: Unregistered equity sale · Item 8.01: Other event
AI summary

Mirum Pharmaceuticals issued $690 million aggregate principal amount of 0.00% Convertible Senior Notes due June 1, 2032 on May 15, 2026, including $90M from full exercise of the purchasers' overallotment option; notes are senior unsecured, bear no cash interest, and carry no principal accretion. Conversion is permitted if the stock exceeds 130% of the conversion price for 20 of 30 consecutive trading days (after Q3 2026), among other triggers; settlement in cash, shares, or a combination at Mirum's option. Items 2.03/3.02 cover the associated debt creation and unregistered sale aspects; Item 8.01 likely covers a related capped call. A major non-dilutive capital raise (at current prices) — $690M of zero-coupon financing provides long-term runway with equity dilution only if the stock appreciates above the conversion premium.

S-3ASRAuto-shelf registrationFeb 25S-3ASR
+ 15 other (4 13Gs · 3 earnings 8-Ks · 2 routine 8-Ks · 2 proxys) in window

Recent news

Latest headlines from major outlets, sourced and timestamped — context for whatever just moved.

Mirum Pharmaceuticals to Announce Second Quarter 2026 Financial Results and Host Conference Call on August 5, 2026businesswire.com·6d agoMirum Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)businesswire.com·22d agoMirum Pharmaceuticals: This Liver Disease Juggernaut Just Broadened Its Portfolioseekingalpha.com·32d agoStrength Seen in Mirum Pharmaceuticals (MIRM): Can Its 5.5% Jump Turn into More Strength?zacks.com·37d agoBiotech ETF Index Surges 10% After Rebalanceetftrends.com·41d ago

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