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AXAXSM

Axsome Therapeutics, Inc.

$AXSM·$12B·Biotechnology·Healthcare
$233.80-6.1%YTD+27.5%1Y+111.1%
Mentions · last 7 days
2026-07-06: 19 posts2026-07-07: 18 posts2026-07-08: 17 posts2026-07-09: 9 posts2026-07-10: 11 posts2026-07-11: 13 posts2026-07-12: 14 posts101+16%
Price updated 2d ago·X counts updated 9h ago
AXAXSM
$AXSMAxsome Therapeutics, Inc.
$233.80-6.09%101 posts+16%
AI analysisFundamentalsVoices on X
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AI verdict & sentimentAI analysisGenerated by AI from underlying data

Top X posts

Today's AI verdict on what's driving $AXSM, plus how loud the X conversation is and which way it's leaning.

AI analysis

TickerTalks’ read on the fundamentals and what’s driving the move.

Driven by hypeAcceleratingAI verdict · as of 2026-07-12

The move is getting stronger, with heavier trading behind it.

Axsome doubled Auvelity's peak-sales guide to $8B — the ADHD label expansion is the whole rerate story.

Axsome Therapeutics is a commercial-stage biotech commercializing Auvelity (dextromethorphan-bupropion) for major depressive disorder plus a broader neuropsychiatric pipeline. The stock is up 111% over the past year on real commercial momentum.

  • Revenue growth is exceptional: $191M last quarter grew 57% YoY, and consensus expects revenue to walk from $985M this year to $2.29B by FY28 with EPS jumping from -$2.12 to $14.92 — the earnings inflection is genuinely material.
  • The margin picture is elite for the category: 93% gross margin reflects Auvelity's premium biologic-like economics — profitability follows as the launch cadence scales.
  • The Auvelity peak-sales guide expansion is the operative catalyst: clean label updates for ADHD enabled peak-sales guidance raised from ~$4B to ~$8B — a doubling of the addressable-market implication, reflecting real regulatory-and-commercial progress.
  • The sales-force expansion to 630 reps is a real operational scale-up with full impact expected in 2H26 — the commercial engine is being built for the ADHD label expansion.
  • The FOCUS-2 and FOCUS-3 Phase 3 Solriamfetol trials in adolescents and children with ADHD add pipeline depth — real Phase 3 progression.
  • Insider prints are a real cluster: officer and director Herriot Tabuteau executed an M-Exempt of $12.18M plus a sale of $11.93M on July 1 at $240.25 — a very large single-day distribution at record-high prices.

The August 3 Q2 earnings print is the near-term catalyst — a beat on Auvelity revenue plus continued ADHD-launch-timeline commentary extends the trajectory. A soft Auvelity print, a specific reimbursement-payer disclosure, or a further Tabuteau-scale insider selling cluster breaks the setup.

Agrees with X sentimentX is bullish on Auvelity's peak-sales guide doubling from ~$4B to ~$8B on the ADHD clean label updates, the completed sales-force expansion to 630 reps with full impact expected in 2H26, and the FOCUS-2 and FOCUS-3 Phase 3 Solriamfetol trials — supported by the mechanics (57% revenue growth, credible EPS turn from -$2.12 to $14.92 by FY28). Where I'd weight materially: officer and director Herriot Tabuteau's $24M single-day activity on July 1 is a very large insider distribution.

What to watch: August 3 Q2 earnings — a beat on Auvelity revenue plus continued ADHD-launch-timeline commentary extends the trajectory. A soft Auvelity print, a specific reimbursement-payer disclosure, or a further Tabuteau-scale insider selling cluster breaks the setup.

On the calendar: 2026-08-03 — Q2 earnings

earnings soonauvelity peak sales doubledadhd label expansionlarge insider selling

X sentiment

What the X crowd is saying right now — descriptive, summarised from the day’s posts.

Bullish sentiment6 posts analyzed · as of 2026-07-02

Axsome Therapeutics is drawing sell-side attention. Oppenheimer hosted management and highlighted accelerating Auvelity momentum in major depressive disorder (Auvelity's clean label updates for ADHD enabled peak sales guidance raised from ~$4B to ~$8B), following a completed sales-force expansion to 630 reps with full impact expected in 2H26. AXSM also initiated the FOCUS-3 Phase 3 trial of Solriamfetol in adolescents with ADHD, randomizing ~468 patients 1:1:1. Only a light bear reference from a prior 'generational short' post; no substantive current bear thread.

Read the AI verdict + X sentiment for $AXSM

  • One-line verdict on what's driving the move — fundamentals, momentum, both, or an event
  • Next dated catalyst when there is one (earnings, deal closing, activist clock)
  • X crowd read with bullish/bearish call + post volume
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What it does

Plain-English summary of the business — what they sell and how they make money.

Commercial CNS biotech with Auvelity approved for major depression and Sunosi for narcolepsy, with CNS pipeline.

Industry overviewAI analysisGenerated by AI from underlying data

Where Biotechnology sits in its cycle right now — and what that implies for $AXSM.

Biotechnology · Healthcare

No material change from last week — ADA conference oral formulation competition is bifurcating biotech multiples between GLP-1 platform holders and precision oncology innovators.

What this means for $AXSM

Partial — Commercial CNS biotech with Auvelity approved for major depression and Sunosi for narcolepsy, with CNS pipeline; the GLP-1 pipeline bifurcation and ADA oral formulation competition creates tailwinds for one product line, not the full operation.

Top industry ETF

$IBBiShares Biotechnology ETF
+13.2%YTD
+43.7%1Y

Fundamentals & catalyst

Profitability, valuation, and the next earnings event — at a glance, with rule-of-thumb signals.

Key ratios

P/E
-63.2How much investors are paying per dollar of profit the company actually earned in the last 12 months. Lower means the stock looks cheaper relative to earnings.~15–25 is typical for the S&P 500; high-growth names trade 30+; hyper-growth or speculative can be 100+ or negative.
ROIC
-50.8%What percentage return the business earns on every dollar of capital (equity + debt) deployed in operations. The cleanest measure of business quality.Above ~15% is high-quality; consistently above 25% suggests a real moat. Below the company's cost of capital is value-destroying.
Op margin
-24.8%Operating profit (after sales, marketing, R&D, and overhead but before interest and taxes) as a percentage of revenue. The clearest view of how well the underlying business is run.Mature business above 20% is healthy; software businesses can run 30%+; commodity / retail businesses operate in single digits.
FCF yield
-0.6%Free cash flow (operating cash flow minus capex) divided by the company's market cap. The cash-on-cash return you'd get owning the whole business at today's price.Above ~5% is attractive; below ~2% means you're paying up for growth. Capital-light businesses (software) run higher than capital-heavy ones (utilities).
P/S
16.9Same idea as P/E but per dollar of revenue. Useful for companies that aren't profitable yet, where P/E is meaningless.Under ~2 is cheap; software / SaaS often runs 8–15; well above 20 implies the market is pricing in very high future growth.
ROE
-260%Net income as a percentage of shareholders' equity. Similar to ROIC but counts only the equity side.Above 20% is strong, but can be inflated by leverage — a heavily indebted company can show high ROE with weak underlying ROIC.
Gross margin
92.6%Revenue minus the direct cost of producing what was sold, as a percentage of revenue. The first read on whether the product is structurally profitable.Software / SaaS is typically 70%+; consumer goods 30–50%; commodity / hardware businesses can be under 20%.
D/E
4.0Total debt divided by shareholders' equity. Measures how much the business runs on borrowed money versus owner capital.Under 1 is conservative; 1–2 is typical for mature businesses; over 2 is leveraged and more sensitive to interest rates.

Past earnings

QuarterReportedActualEstimateSurprise
Q1 2026May 4, 2026$-1.26$-0.85-48.2%
Q4 2025Feb 23, 2026$-0.71$-0.70-1.4%
Q3 2025Nov 3, 2025$-0.94$-0.82-14.6%
Q2 2025Aug 4, 2025$-0.92$-1.00+8.0%
Next earningsMon, Aug 3·consensus EPS $-0.86

Quarterly trend

QuarterRevenueYoYGrossOpEPSFCF
Q1 FY26$191.2M+57.4%92.3%-33.1%$-1.26$-20.8M
Q4 FY25$196.0M+65.0%93.7%-15.0%$-0.56$-18.7M
Q3 FY25$171.0M+63.2%93.0%-27.0%$-0.94$988K
Q2 FY25$150.0M+72.1%91.0%-24.5%$-0.97$-32.4M

Forward consensus

5-year forecast · up to 17 analysts
FYRevenueRangeEPSRangeAnalysts
FY26$984.8M$868.8M – $1.1B-$2.12-$6.06 – -$0.0616
FY27$1.6B$1.2B – $1.8B$5.52-$8.19 – $10.4616
FY28$2.3B$2.3B – $2.3B$14.92-$4.23 – $33.3917
FY29$3.1B$2.6B – $3.7B$25.50$20.03 – $31.5814
FY30$3.8B$3.2B – $4.5B$32.55$25.56 – $40.308

Setup & momentum

Volume, range, and moving-average position — the technical setup driving short-term moves.

Right now

Vol vs 30dToday's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.0.6×Today's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.
52w rangeWhere the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.93%Where the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.
vs 50d MALatest close vs the 50-day simple moving average. Positive = short-term trend is up.+6.6%Latest close vs the 50-day simple moving average. Positive = short-term trend is up.
vs 200d MALatest close vs the 200-day simple moving average. Positive = long-term trend is up.+41.4%Latest close vs the 200-day simple moving average. Positive = long-term trend is up.

Float & profile

FloatLow float · 43.6M shFree-float shares — the slice of issued stock actually available to trade. Lower buckets squeeze harder on a catalyst.Traded today1.4% of floatToday's volume as a percent of the free float. Above 5% on a single day is unusually high turnover for the available share count.

Insider activity

Recent open-market buys and sells by officers and directors — flagged when multiple insiders cluster.

Recent transactions

SellJul 1Herriot TabuteauCEO49.7K sh$11.9MSellJun 11Roger JeffsDirector286 sh$71KSellJun 10Roger JeffsDirector286 sh$70KSellJun 10Susan MahonyDirector300 sh$74KSellJun 10Mark ColemanDirector643 sh$160KSellJun 9Susan MahonyDirector300 sh$71KSellJun 9Nick PizzieCFO33.0K sh$7.9MSellJun 9Herriot TabuteauCEO49.7K sh$12.0MSellJun 2Mark ColemanDirector5.5K sh$1.2MSellJun 1Mark ColemanDirector6.0K sh$1.4M
1–10 of 19
+ 31 other (17 exempts · 14 awards) in window

See when $AXSM insiders are putting their own money in

  • Real-time open-market buys and sells from Form 4 filings
  • Cluster-buy detection when multiple insiders pile in at once
  • 30 / 60 / 180-day windows so you can spot building conviction
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SEC filings

Material 8-K, 13D, S-3, and 424B5 events from the last 180 days — the filings that actually move the price.

Recent material filings

8-KOfficer or director changeJun 98-K — Item 5.02: Officer or director change
AI summary

Axsome Therapeutics adopted a new Executive Severance Plan effective June 9, 2026, superseding all prior severance plans and individual employment agreement severance terms. Under the plan, Tier 1 (CEO) receives 18 months of base salary upon involuntary termination (including good reason resignation); Tier 2 (other Section 16 officers) receives 12 months; Tier 3 (VPs and above) receives 6 months — each paid in equal installments over the applicable period, with enhanced terms during a Change in Control period. The plan standardizes severance terms across Axsome's management tier, representing a governance improvement with modest incremental financial exposure.

8-KShareholder voteJun 98-K — Item 5.07: Shareholder vote
AI summary

Axsome Therapeutics held its 2026 Annual Meeting with 43,777,536 of 51,439,952 eligible shares represented (~85.1% quorum). Class II directors Mark Saad (28.7M for, 10.3M withheld — ~27% withhold rate) and Susan Mahony, Ph.D. (29.9M for, 9.1M withheld — ~23% withhold rate) were elected for terms through the 2029 annual meeting; Deloitte & Touche LLP was ratified as independent auditor for FY2026. A non-binding say-on-pay proposal was also voted on but results are truncated in the excerpt. The elevated withhold rates (~27% and ~23%) on both director nominees are above typical levels and merit monitoring.

+ 12 other (4 routine 8-Ks · 2 proxys · 1 10-Q · 1 8-K) in window

Recent news

Latest headlines from major outlets, sourced and timestamped — context for whatever just moved.

3 Under-the-Radar Stocks to Buy and Holdfool.com·3d agoBetter Growth Buy: Axsome vs Revolution Medicinesfool.com·4d agoAxsome Begins Phase III Study on Solriamfetol for ADHD in Childrenzacks.com·5d agoAxsome Therapeutics Initiates FOCUS-2 Phase 3 Trial of Solriamfetol in Children with Attention Deficit Hyperactivity Disorder (ADHD)globenewswire.com·6d agoThese 3 Stocks Trounced the S&P 500 in the First Half of 2026 -- and Wall Street Thinks 1 of Them Could Soar Even Morefool.com·7d ago

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