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ANANRO

Alto Neuroscience, Inc.

$ANRO·$930M·Biotechnology·Healthcare
$26.41-0.9%YTD+48.5%1Y+564.8%
Price updated 7m ago·X counts updated 2d ago
ANANRO
$ANROAlto Neuroscience, Inc.
$26.42-0.92%1 posts
AI analysisFundamentalsVoices on X
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On X

The complete picture of $ANRO on X — how loud the conversation is right now, how it has trended over the last two weeks, and which way the crowd is leaning.

1X posts · last 7 days
Sep 11Sep 27

AI verdictAI analysisGenerated by AI from underlying data

TickerTalks' own read on what's driving $ANRO — fundamentals, momentum, or an event — and whether it agrees with the X crowd.

Driven by hypeWinding up for a moveAI verdict · as of 2026-09-28

Trading in a tight range and building pressure — a move looks likely soon, but the direction isn't clear yet.

Alto Neuroscience +597% t12m; precision-psychiatry biomarker platform; PT $37.25 average; Nick Smith promoted to President + CFO.

ANRO is the massive biotech multi-bagger consolidating after an extraordinary run — biomarker-guided psychiatry is the story.

  • Tape: +47.6% YTD, +597.1% t12m; 69% of 52w range, -12.4% vs 50-day, +16.2% vs 200-day.
  • Average analyst PT $37.25 vs $26.49 spot (~40% upside).
  • Nick Smith promoted to President + CFO effective 8/26; CEO Amit Etkin retains CEO role only.
  • Q2 EPS -$0.65 vs -$0.735 (+11.5%); FY26 est EPS -$2.78, FY29 -$3.00.
  • PE -14.7x (loss), no revenue base; op margin 0; D/E 0.03 (essentially unlevered).
  • AWM Investment Company took new position.
  • Float 35.1M; beta 1.16.
  • No X sentiment sample.

Watch 11/11 print for pipeline milestones and any biomarker-registration data disclosure.

What to watch: 11/11 earnings, biomarker registration data, pipeline milestones, and any partnership or M&A activity.

On the calendar: 2026-11-11

sentiment missing

Read the AI verdict on $ANRO

  • One-line verdict on what's driving the move — fundamentals, momentum, both, or an event
  • Next dated catalyst when there is one (earnings, deal closing, activist clock)
  • Whether TickerTalks' read agrees with or diverges from the X crowd
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What it does

Plain-English summary of the business — what they sell and how they make money.

Clinical-stage biopharma using AI biomarkers to develop precision psychiatry drugs for treatment-resistant depression and PTSD.

Industry overviewAI analysisGenerated by AI from underlying data

Where Biotechnology sits in its cycle right now — and what that implies for $ANRO.

Biotechnology · Healthcare

No material change from last week — mRNA oncology platform remains the structural driver.

What this means for $ANRO

Neutral — Clinical-stage biopharma using AI biomarkers to develop precision psychiatry drugs for treatment-resistant depression and PTSD.

Top industry ETF

$IBBiShares Biotechnology ETF
+24.2%YTD
+48.0%1Y

Fundamentals & catalyst

Profitability, valuation, and the next earnings event — at a glance, with rule-of-thumb signals.

Key ratios

P/E
-14.7How much investors are paying per dollar of profit the company actually earned in the last 12 months. Lower means the stock looks cheaper relative to earnings.~15–25 is typical for the S&P 500; high-growth names trade 30+; hyper-growth or speculative can be 100+ or negative.
ROIC
18.4%What percentage return the business earns on every dollar of capital (equity + debt) deployed in operations. The cleanest measure of business quality.Above ~15% is high-quality; consistently above 25% suggests a real moat. Below the company's cost of capital is value-destroying.
Op margin
0.0%Operating profit (after sales, marketing, R&D, and overhead but before interest and taxes) as a percentage of revenue. The clearest view of how well the underlying business is run.Mature business above 20% is healthy; software businesses can run 30%+; commodity / retail businesses operate in single digits.
FCF yield
-5.4%Free cash flow (operating cash flow minus capex) divided by the company's market cap. The cash-on-cash return you'd get owning the whole business at today's price.Above ~5% is attractive; below ~2% means you're paying up for growth. Capital-light businesses (software) run higher than capital-heavy ones (utilities).
P/S
0.0Same idea as P/E but per dollar of revenue. Useful for companies that aren't profitable yet, where P/E is meaningless.Under ~2 is cheap; software / SaaS often runs 8–15; well above 20 implies the market is pricing in very high future growth.
ROE
-46.5%Net income as a percentage of shareholders' equity. Similar to ROIC but counts only the equity side.Above 20% is strong, but can be inflated by leverage — a heavily indebted company can show high ROE with weak underlying ROIC.
Gross margin
0.0%Revenue minus the direct cost of producing what was sold, as a percentage of revenue. The first read on whether the product is structurally profitable.Software / SaaS is typically 70%+; consumer goods 30–50%; commodity / hardware businesses can be under 20%.
D/E
0.0Total debt divided by shareholders' equity. Measures how much the business runs on borrowed money versus owner capital.Under 1 is conservative; 1–2 is typical for mature businesses; over 2 is leveraged and more sensitive to interest rates.

Past earnings

QuarterReportedActualEstimateSurprise
Q2 2026Aug 12, 2026$-0.65$-0.73+11.5%
Q1 2026May 13, 2026$-0.80$-0.56-42.9%
Q4 2025Mar 16, 2026$-0.45$-0.56+19.6%
Q3 2025Nov 12, 2025$-0.52$-0.66+21.2%
Next earningsWed, Nov 11·consensus EPS $-0.67

Quarterly trend

QuarterRevenueYoYGrossOpEPSFCF
Q2 FY26$0———$-0.65$-19.8M
Q1 FY26$0———$-0.80$-27.6M
Q4 FY25$0———$-0.51$-11.5M
Q3 FY25$0———$-0.52$-9.9M

Forward consensus

5-year forecast · up to 6 analysts
FYRevenueRangeEPSRangeAnalysts
FY26$0$0 – $0-$2.78-$2.96 – -$2.470
FY27$0$0 – $0-$3.07-$3.91 – -$1.920
FY28$6.2M$6.2M – $6.2M-$3.05-$4.39 – -$2.196
FY29$40.6M$40.6M – $40.6M-$3.00-$3.00 – -$3.004
FY30$216.7M$216.7M – $216.7M-$0.65-$0.65 – -$0.653

Setup & momentum

Volume, range, and moving-average position — the technical setup driving short-term moves.

Right now

Vol vs 30dToday's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.1.1×Today's traded share volume divided by the average over the prior 30 trading days. ≥3× signals unusual interest; below 1× is quiet.
52w rangeWhere the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.68%Where the latest close sits between the 52-week low (0%) and high (100%). Above 80% is extended; below 30% is basing or in a downtrend.
vs 50d MALatest close vs the 50-day simple moving average. Positive = short-term trend is up.-14.0%Latest close vs the 50-day simple moving average. Positive = short-term trend is up.
vs 200d MALatest close vs the 200-day simple moving average. Positive = long-term trend is up.+13.4%Latest close vs the 200-day simple moving average. Positive = long-term trend is up.

Float & profile

FloatLow float · 35.1M shFree-float shares — the slice of issued stock actually available to trade. Lower buckets squeeze harder on a catalyst.Traded today1.7% of floatToday's volume as a percent of the free float. Above 5% on a single day is unusually high turnover for the available share count.β1.165-year weekly beta vs the S&P 500. Above 1.5 means the stock typically moves more than the index; below 0.8 moves less.FilingActive offeringA shelf registration (S-3 / S-3ASR / S-1) or prospectus supplement (424B*) was filed in the last 90 days — the company is registered to (or actively) issuing new shares. Dilution risk.

Insider activity

Recent open-market buys and sells by officers and directors — flagged when multiple insiders cluster.

Recent transactions

No open-market buys or sells in the last 180 days.

+ 7 other (6 awards · 1 gift) in window

See when $ANRO insiders are putting their own money in

  • Real-time open-market buys and sells from Form 4 filings
  • Cluster-buy detection when multiple insiders pile in at once
  • 30 / 60 / 180-day windows so you can spot building conviction
Free, forever. No credit card.

SEC filings

Material 8-K, 13D, S-3, and 424B5 events from the last 180 days — the filings that actually move the price.

Recent material filings

8-KOfficer or director changeAug 278-K — Item 5.02: Officer or director change
AI summary

Alto Neuroscience promoted Nicholas C. Smith from CFO and CBO to President and CFO of the company, effective August 26, 2026. CEO Amit Etkin, M.D., Ph.D. relinquishes the President title but continues as Chief Executive Officer and principal executive officer. Administrative leadership restructuring; Smith now serves as both president and principal financial officer.

8-KMaterial agreementJul 148-K — Item 1.01: Material agreement
AI summary

Alto Neuroscience, Inc. (ANRO, Mountain View CA) filed a current report on July 13, 2026 (filed July 14) disclosing entry into a material definitive agreement (Item 1.01) with exhibits. A new material agreement for a precision psychiatry company may signal a licensing deal, research collaboration, pharma partnership, or financing arrangement. The specific agreement terms are in attached exhibits.

424B5Prospectus supplement (offering)Jul 14424B5
AI summary

Alto Neuroscience, Inc. (ANRO, NYSE) filed a 424B5 prospectus supplement on July 14, 2026 for the registered direct offering of 3,776,436 shares of common stock ($0.0001 par value) at a fixed price of $26.48 per share — equal to the last reported sale price on July 10, 2026 — raising approximately $100 million in gross proceeds. ANRO is an emerging growth company and smaller reporting company. This is live equity dilution; proceeds are intended for clinical development and operations. The offering follows the concurrent Item 1.01 material agreement, suggesting the equity raise may relate to a partnership capital call or clinical advancement funding.

3New insider — initial holdingsMay 293
8-KOfficer or director changeMay 288-K — Item 5.02: Officer or director change
8-KOfficer or director changeMay 138-K — Item 5.02: Officer or director change · Item 5.07: Shareholder vote
S-3Shelf registrationApr 10S-3
+ 17 other (9 13Gs · 2 10-Qs · 2 earnings 8-Ks · 1 8-K) in window

Recent news

Latest headlines from major outlets, sourced and timestamped — context for whatever just moved.

Alto Neuroscience Announces Participation in Upcoming Investor Conferencesgurufocus.com·20d agoAlto Neuroscience Announces Participation in Upcoming Investor Conferencesbusinesswire.com·20d agoAlto Neuroscience, Inc. (NYSE:ANRO) Receives $37.25 Average PT from Analystsdefenseworld.net·30d agoAlto Neuroscience Promotes Nick Smith to President and Chief Financial Officerbusinesswire.com·33d agoAWM Investment Company Inc. Purchases New Holdings in Alto Neuroscience, Inc. $ANROdefenseworld.net·34d ago

In themes

Explore the broader themes this ticker is being talked about under.

AI Precision Medicine

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Voices on X · last 7 days

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